Add pesistence static route In this case the interface is called eth0. Same procedure with bonded interfaces. Eg. bond0 /etc/sysconfig/network-scripts/route-eth0: GATEWAY0=192.168.1.254 NETMASK0=255.255.255.0 ADDRESS0=192.168.55.0 GATEWAY1=10.164.234.112 NETMASK1= 255.255.255.240 ADDRESS1=10.164.234.132 Alternative use this notation in route-eth0: 192.168.55.0/24 via 192.168.1.254 In order to add route restart network service: service network restart